NAD+ precursors have demonstrated great value because they have been shown to boost NAD+, which is a hot topic in the research world. NAD+ is found in all living cells and is essential in important body functions. Energy is vital to staying healthy and to enjoy life. Cellular energy from food is necessary to perform all its functions including work, exercise and daily activities. NAD+ works intracellularly to make ATP energy for the brain, the lungs, the heart and blood vessels, for immune function and repairing critically important DNA. Research has been shown that it helps slow down the aging process among other health advantages.

NAD+ (nicotinamide adenine dinucleotide) is a molecule found in all living cells of the human body. Its needed for energy metabolism converting fuel from food into cellular energy, which gives the power to contract muscles, circulate the blood, and other bodily functions.

NAD+ precursors trigger NAD+ to be made, which provides many benefits to the human body. A few food sources of NAD+ are some types of fish such as salmon, tuna and sardines and also mushrooms, but may be hard to consume on a daily basis.

A few compounds that are NAD+ precursors are Nicotinamide mononucleotide (NMN), Nicotinamide riboside (NR), nicotinamide (NAM), and nicotinic acid (NA). Research shows these precursors help stop the loss of NAD+ during the aging process and in particular health conditions (Braidy N, et al, 2018). They are believed to have an essential protective effect.

Nicotinamide mononucleotide (NMN) one of the precursors, is a nucleotide. The body’s enzymes use NMN to manufacture the important, nicotinamide adenine dinucleotide (NADH)

  • NMN provides support to the body’s genetic material called DNA and assists in its repair. This is so important because DNA provides the instructions to manage all the cells in the body. Keeping DNA healthy is critical to a long and healthy life.
  • NMN has shown numerous physiological mechanisms, which demonstrate that it has benefits (Poddar SK et al, 2019). It is involved in cellular activity, protects the heart and has demonstrated support for the brain, blood sugar and weight management and longevity.
  • Animal research shows that NMN promotes the synthesis of NAD+ (Mills KF, et al, 2016).

Absorption and Conversion of Precursors into NAD+ in the body

NMN has been shown to help boost the levels of NAD+ to rise in the body.

  • One animal study showed that providing NMN in the diet was rapidly used to make NAD+ in the tissues (Mills KF, et al, 2016).
  • By providing NMN, the signs of the aging process were delayed including improvement of energy metabolism and eye function; reduced the tendency to gain weight and provided support for blood sugar and cholesterol.
  • Another NAD+ precursor Nicotinamide riboside (NR) in a single dose has been shown in humans to raise blood NAD+ up to 2.7-fold (Trammell SA, et al, 2016)

In summary, NAD+ precursors have the ability to boost NAD+ levels, which is necessary for making ATP energy to help the body perform all of its important functions. In addition, NAD+ precursors help to reduce the decline of NAD+ during the aging process and during certain health conditions.